Stefano Bovino - March 11, 2016 Modelling the microphysics in low-metallicity star-forming regions Understanding how metal poor stars were formed is of fundamental importance to probe the chemical and physical conditions of primordial stars, and contributes to improve our knowledge on the transition between the first (PopIII) and the second (PopII) generation of stars in the Universe. Compared to the formation of Pop III stars, where the chemistry is simple, for the second generation of stars the presence of dust, metals, and feedback adds complexity which results in a high computational cost and large uncertainties. An accurate treatment of the dust and metal physics is needed. We have employed the astrochemistry package KROME coupled with the hydrodynamical code ENZO to explore the conditions under which such stars were formed. In this talk I will present results from recent simulations of low-metallicity star-forming regions and discuss the effects of the grain size distribution on the thermal evolution and the dynamical properties of the collapsing haloes.